Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | CHKA | P35790 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPM1 | P06748 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484370 | 0.81 | PIM1 (0.40) | PIM1PIM3FYNDGAT1ACVRL1 | |
| SCHEMBL29538822 | 0.81 | PIM1 (0.40) | PIM1PIM3FYNDGAT1ACVRL1 | |
| SCHEMBL21484350 | 0.79 | PIM1 (0.40) | PIM1PIM3HRH3FYNDGAT1 | |
| SCHEMBL19951691 | 0.74 | MELK (0.39) | APPCHKAHRH3DGAT1ALK | |
| SCHEMBL21484391 | 0.70 | EGFR (0.44) | PIM1PIM3FYN | |
| SCHEMBL21484319 | 0.70 | EGFR (0.39) | PIM1PIM3FYNSMN1; SMN2RAB9A | |
| SCHEMBL19950721 | 0.69 | ALK (0.44) | HRH3DGAT1ACVRL1ACVR1ALK | |
| SCHEMBL19950416 | 0.68 | ALK (0.41) | HRH3DGAT1ACVRL1ACVR1ALK | |
| SCHEMBL30070358 | 0.68 | ALK (0.41) | HRH3DGAT1ACVRL1ACVR1ALK | |
| SCHEMBL18440623 | 0.68 | DGAT1 (0.37) | CHKAHRH3DGAT1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072865-B | Pyrrolo-aromatic heterocyclic compounds, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-02-11 | — | — | CN | disclosed |