Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 9/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.35 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21484370 | 1.00 | PIM1 (0.40) | PIM1PIM3CDC7CDK9BRD4 | |
| SCHEMBL21484350 | 0.84 | PIM1 (0.40) | PIM1PIM3CDC7CDK9ALK | |
| SCHEMBL21484391 | 0.81 | EGFR (0.44) | PIM1PIM3CDK9BRD4FYN | |
| SCHEMBL28700796 | 0.81 | PIM1 (0.37) | PIM1PIM3ALKFYNDGAT1 | |
| SCHEMBL21758128 | 0.75 | EGFR (0.54) | ALK | |
| SCHEMBL21484332 | 0.73 | MAPKAPK2 (0.41) | BRD4 | |
| SCHEMBL21484319 | 0.73 | EGFR (0.39) | PIM1PIM3LCKMAP4K1FYN | |
| SCHEMBL1356795 | 0.73 | PDE1B (0.36) | — | |
| SCHEMBL17289763 | 0.73 | TBK1 (0.34) | PIM1PIM3CDC7CDK9ALK | |
| SCHEMBL1354772 | 0.72 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110072865-B | Pyrrolo-aromatic heterocyclic compounds, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2022-02-11 | — | — | CN | disclosed |