Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28719788 | 0.92 | MAOB (0.53) | KMT2AMAOBNPC1RAB9ARECQL | |
| SCHEMBL3772763 | 0.77 | KMT2A (1.00) | KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7814459 | 0.75 | MAOB (0.54) | KMT2AMAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL11728742 | 0.75 | MAOB (0.54) | KMT2AMAOBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15709504 | 0.74 | NPC1 (0.60) | KMT2AMAOBNPC1RAB9ARECQL | |
| SCHEMBL5045755 | 0.74 | NPC1 (0.60) | KMT2AMAOBNPC1RAB9ARECQL | |
| SCHEMBL11219615 | 0.74 | MAOB (0.53) | KMT2AMAOBNPC1RAB9AALDH1A1 | |
| SCHEMBL2443481 | 0.72 | KMT2A (0.68) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL13912376 | 0.72 | KMT2A (0.68) | KMT2ANPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL14757597 | 0.71 | MAOB (0.57) | KMT2AMAOBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213307-A | Preparation method of N-alkyl substituted pyrrolidone compound | 河南农业大学 | 2022-03-22 | — | — | CN | disclosed |