Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.74 |
| ▸ | POLB | P06746 | 7/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.74 |
| ▸ | LDHA | P00338 | 1/20 | 0.59 |
| ▸ | LDHB | P07195 | 1/20 | 0.59 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | STAT1 | P42224 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554180 | 0.85 | POLB (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2557746 | 0.84 | KDM4E (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6386980 | 0.83 | POLB (0.65) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL2558163 | 0.76 | KDM4E (0.58) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL396870 | 0.75 | ALDH1A1 (0.80) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6415208 | 0.74 | ALDH1A1 (0.76) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1435328 | 0.74 | LDHA (0.78) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1435313 | 0.74 | LDHA (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL30343475 | 0.74 | LDHA (1.00) | KDM4EPOLBALDH1A1TDP1L3MBTL1 | |
| SCHEMBL622653 | 0.74 | KDM4E (0.66) | KDM4EPOLBALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213236-A | Synthesis of Yeast dehydrogenase inhibitors | 上海寻科生物医药科技有限公司 | 2022-03-22 | — | — | CN | disclosed |