SCHEMBL28700910

SCHEMBL28700910

O=[N+]([O-])C1(Br)CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KCNA4 P22459 2/20 0.45
KCNA1 Q09470 2/20 0.45
KCNAB1 Q14722 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687804 0.75 KCNA4 (0.45) KCNA4KCNA1KCNAB1
SCHEMBL9452643 0.74 KCNA4 (0.43) KCNA4KCNA1KCNAB1
SCHEMBL15642971 0.73 KCNA4 (0.44) KCNA4KCNA1KCNAB1
SCHEMBL97282 0.70 KCNA4 (0.56) KCNA4KCNA1KCNAB1
Cyclohexane SCHEMBL28752636 0.67 KCNA4 (0.52) KCNA4KCNA1KCNAB1
SCHEMBL27968826 0.62
SCHEMBL10447506 0.62 KCNA4 (1.00) KCNA4KCNA1KCNAB1
SCHEMBL2465011 0.60 KCNA4 (0.40) KCNA4KCNA1KCNAB1
Dioxane SCHEMBL5805799 0.60 CA5A (0.57)
Dioxane SCHEMBL27608979 0.60 TTR (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114213254-B Beta-nitroketone and preparation method and application method thereof 北京师范大学 2023-04-25 CN disclosed
CN-114213254-A Beta-nitroketone, and preparation method and application method thereof 北京师范大学 2022-03-22 CN disclosed