Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 9/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 6/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31144052 | 1.00 | HCRTR2 (0.38) | HCRTR2HCRTR1TSHRRETGRIN2D | |
| SCHEMBL26919352 | 0.76 | ACACB (0.39) | HCRTR2HCRTR1RETGRIN2DGRIN3B | |
| SCHEMBL20959095 | 0.73 | ALDH1A1 (0.44) | HCRTR2HCRTR1TSHR | |
| Hydrochloric Acid SCHEMBL31144002 | 0.72 | FURIN (0.37) | HCRTR2TSHR | |
| Hydrochloric Acid SCHEMBL28713483 | 0.72 | FURIN (0.37) | HCRTR2TSHR | |
| SCHEMBL28840055 | 0.72 | GRIN2D (0.41) | HCRTR2HCRTR1RETGRIN2DGRIN3B | |
| SCHEMBL29782901 | 0.71 | PDE10A (0.48) | RETGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL29749185 | 0.71 | PDE10A (0.41) | RETACACB | |
| SCHEMBL29782960 | 0.70 | ACACB (0.40) | HCRTR2HCRTR1RETACACB | |
| SCHEMBL11356194 | 0.66 | GRIN2D (0.56) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |