Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29137079 | 0.95 | TLR8 (0.44) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL29137074 | 0.88 | TLR8 (0.39) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| Bromide SCHEMBL28540808 | 0.88 | L3MBTL1 (0.41) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL27942970 | 0.82 | L3MBTL1 (0.47) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL6833232 | 0.81 | TLR8 (0.55) | TLR8ALDH1A1POLBKMT2AKDM4E | |
| SCHEMBL30716886 | 0.80 | EPHX1 (0.35) | TLR8L3MBTL1KMT2AKDM4EMAPT | |
| Hydrochloric Acid SCHEMBL25338117 | 0.80 | L3MBTL1 (0.46) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| Water SCHEMBL31566367 | 0.80 | L3MBTL1 (0.46) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| Bromide SCHEMBL28223816 | 0.80 | L3MBTL1 (0.46) | TLR8L3MBTL1ALDH1A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL27953560 | 0.80 | L3MBTL1 (0.46) | TLR8L3MBTL1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113933431-B | Method for determining alkaloid in main stream smoke of cigarettes | 中国烟草总公司郑州烟草研究院 | 2023-09-01 | — | — | CN | claimed |
| CN-113933432-B | High-sensitivity and high-precision analysis method suitable for detecting alkaloid in tobacco leaves | 中国烟草总公司郑州烟草研究院 | 2023-08-25 | — | — | CN | claimed |
| CN-113933432-A | High-sensitivity and high-precision analysis method suitable for detecting alkaloid in tobacco leaves | 中国烟草总公司郑州烟草研究院 | 2022-01-14 | — | — | CN | claimed |
| CN-113933431-A | Method for measuring alkaloid in cigarette mainstream smoke | 中国烟草总公司郑州烟草研究院 | 2022-01-14 | — | — | CN | claimed |
| CN-113933431-B | Method for determining alkaloid in main stream smoke of cigarettes | 中国烟草总公司郑州烟草研究院 | 2023-09-01 | — | — | CN | disclosed |
| CN-113933432-B | High-sensitivity and high-precision analysis method suitable for detecting alkaloid in tobacco leaves | 中国烟草总公司郑州烟草研究院 | 2023-08-25 | — | — | CN | disclosed |
| CN-113933432-A | High-sensitivity and high-precision analysis method suitable for detecting alkaloid in tobacco leaves | 中国烟草总公司郑州烟草研究院 | 2022-01-14 | — | — | CN | disclosed |
| CN-113933431-A | Method for measuring alkaloid in cigarette mainstream smoke | 中国烟草总公司郑州烟草研究院 | 2022-01-14 | — | — | CN | disclosed |