Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28702194 | 0.88 | TLR8 (0.41) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| SCHEMBL29137079 | 0.86 | TLR8 (0.44) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| Glycine SCHEMBL31228162 | 0.86 | SMN1; SMN2 (0.40) | L3MBTL1KDM4ECYP2D6MAPTKMT2A | |
| Bromide SCHEMBL28223816 | 0.85 | L3MBTL1 (0.46) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| SCHEMBL27942970 | 0.83 | L3MBTL1 (0.47) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| Hydrochloric Acid SCHEMBL25338117 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| Water SCHEMBL31566367 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| Hydrochloric Acid SCHEMBL27953560 | 0.81 | L3MBTL1 (0.46) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| Bromide SCHEMBL31511741 | 0.80 | L3MBTL1 (0.45) | L3MBTL1KDM4ECYP2D6LPOTLR8 | |
| SCHEMBL28577467 | 0.80 | MAPT (0.42) | TLR8MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112552648-B | Three-dimensional ordered controllable carbon fiber heat-conducting composite material and preparation method thereof | 安徽大学 | 2022-05-10 | — | — | CN | claimed |
| CN-109370569-B | Preparation method of carbon-containing quantum dot white light emitting room temperature ionic liquid | 山东大学 | 2021-05-11 | — | — | CN | claimed |
| CN-112552648-A | Three-dimensional ordered controllable carbon fiber heat-conducting composite material and preparation method thereof | 安徽大学 | 2021-03-26 | — | — | CN | claimed |
| CN-112552648-B | Three-dimensional ordered controllable carbon fiber heat-conducting composite material and preparation method thereof | 安徽大学 | 2022-05-10 | — | — | CN | disclosed |
| CN-109370569-B | Preparation method of carbon-containing quantum dot white light emitting room temperature ionic liquid | 山东大学 | 2021-05-11 | — | — | CN | disclosed |
| CN-112552648-A | Three-dimensional ordered controllable carbon fiber heat-conducting composite material and preparation method thereof | 安徽大学 | 2021-03-26 | — | — | CN | disclosed |