Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.46 |
| ▸ | DRD4 | P21917 | 6/20 | 0.44 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13452487 | 0.84 | DRD4 (0.60) | HRH3DRD4 | |
| SCHEMBL22588657 | 0.78 | HRH3 (0.45) | HRH3DRD4EPHA2IRAK4ERBB2 | |
| SCHEMBL28689656 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL12191227 | 0.77 | HRH3 (0.70) | HRH3DRD4 | |
| SCHEMBL29483718 | 0.74 | DRD4 (0.65) | HRH3DRD4 | |
| SCHEMBL24782354 | 0.73 | PDE5A (0.46) | — | |
| SCHEMBL10629339 | 0.73 | HRH3 (0.43) | HRH3DRD4EPHA2 | |
| SCHEMBL10629334 | 0.73 | HRH3 (0.43) | HRH3DRD4EPHA2 | |
| SCHEMBL17166482 | 0.73 | HRH3 (0.61) | HRH3DRD4 | |
| SCHEMBL14208023 | 0.72 | HRH3 (0.68) | HRH3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127064-A | 4H-pyrrolo [3,2-c ] pyridin-4-one compounds | 拜耳股份有限公司 | 2022-03-01 | — | — | CN | disclosed |