Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 5/20 | 0.39 |
| ▸ | IGF1R | P08069 | 4/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 7/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27275335 | 0.92 | IGF1R (0.43) | JAK1JAK2IGF1RTBK1BTK | |
| SCHEMBL29754196 | 0.92 | IGF1R (0.43) | JAK1JAK2IGF1RTBK1BTK | |
| SCHEMBL30891576 | 0.87 | JAK3 (0.36) | JAK1JAK2IGF1RTBK1BTK | |
| SCHEMBL29754145 | 0.83 | IGF1R (0.48) | IGF1R | |
| SCHEMBL22544824 | 0.83 | IGF1R (0.48) | IGF1R | |
| SCHEMBL22546070 | 0.81 | TBK1 (0.47) | JAK1JAK2TBK1 | |
| SCHEMBL29754256 | 0.81 | TBK1 (0.47) | JAK1JAK2TBK1 | |
| SCHEMBL22544565 | 0.79 | CDK4 (0.47) | JAK1JAK2IGF1RTBK1 | |
| SCHEMBL29754131 | 0.79 | CDK4 (0.47) | JAK1JAK2IGF1RTBK1 | |
| SCHEMBL27275338 | 0.78 | IGF1R (0.46) | JAK1JAK2IGF1RTRPC3TRPC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113993861-B | Phenyl ethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-113993861-A | Phenylethers and anilines of pyrazolyl-amino-pyrimidinyl derivatives and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2022-01-28 | — | — | CN | disclosed |