Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956618 | 0.84 | ALDH1A1 (0.48) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL4073891 | 0.84 | ALDH1A1 (0.48) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL12028942 | 0.84 | ALDH1A1 (0.48) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL28705342 | 0.82 | ALDH1A1 (0.36) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL2557114 | 0.81 | ALDH1A1 (0.46) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL2554121 | 0.81 | ALDH1A1 (0.46) | MIFALDH1A1PTGS2NOS2NOS3 | |
| SCHEMBL3627285 | 0.77 | SLC13A5 (0.46) | ALDH1A1PTGS2 | |
| SCHEMBL3627288 | 0.77 | SLC13A5 (0.46) | ALDH1A1PTGS2 | |
| SCHEMBL28696421 | 0.77 | KIF11 (0.33) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL540304 | 0.76 | ALDH1A1 (0.46) | ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |