Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 7/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 7/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29386850 | 1.00 | KCNK3 (0.59) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL28684553 | 0.87 | PTPN1 (0.53) | KCNK3KCNK9KMT2AMEN1POLB | |
| SCHEMBL28704826 | 0.86 | RAB9A (0.59) | KMT2AMEN1POLBNPC1RAB9A | |
| SCHEMBL28708129 | 0.85 | KCNK3 (0.59) | KCNK3KCNK9KMT2AMEN1NPC1 | |
| SCHEMBL29387093 | 0.85 | RAB9A (0.51) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL29389710 | 0.85 | KCNK3 (0.59) | KCNK3KCNK9KMT2AMEN1NPC1 | |
| SCHEMBL28690660 | 0.85 | NPC1 (0.60) | KCNK3KMT2AMEN1POLBNPC1 | |
| SCHEMBL29389334 | 0.85 | NPC1 (0.60) | KCNK3KMT2AMEN1POLBNPC1 | |
| SCHEMBL28691389 | 0.85 | RAB9A (0.51) | KMT2AMEN1NPC1RAB9ATP53 | |
| SCHEMBL28706305 | 0.84 | NPC1 (0.64) | KCNK3KCNK9KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |