Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.59 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29389710 | 1.00 | KCNK3 (0.59) | KCNK3KCNK9MAPTMEN1HTT | |
| SCHEMBL28684553 | 0.87 | PTPN1 (0.53) | KCNK3KCNK9MAPTMEN1HTT | |
| SCHEMBL28704838 | 0.86 | F10 (0.59) | MAPTMEN1HTTKMT2ARAB9A | |
| SCHEMBL29386850 | 0.85 | KCNK3 (0.59) | KCNK3KCNK9MEN1KMT2ARAB9A | |
| SCHEMBL28691389 | 0.85 | RAB9A (0.51) | MAPTMEN1HTTKMT2ARAB9A | |
| SCHEMBL28704845 | 0.85 | KCNK3 (0.59) | KCNK3KCNK9MEN1KMT2ARAB9A | |
| SCHEMBL29389334 | 0.85 | NPC1 (0.60) | KCNK3MAPTMEN1HTTKMT2A | |
| SCHEMBL29387093 | 0.85 | RAB9A (0.51) | MAPTMEN1HTTKMT2ARAB9A | |
| SCHEMBL28690660 | 0.85 | NPC1 (0.60) | KCNK3MAPTMEN1HTTKMT2A | |
| SCHEMBL28698368 | 0.83 | LMNA (0.66) | KCNK3KCNK9MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | claimed |
| CN-114057630-B | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-114057630-A | Pirfenidone derivative and synthetic method and application thereof | 郑州大学 | 2022-02-18 | — | — | CN | disclosed |