Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2589792 | 0.80 | MEN1 (0.68) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2589796 | 0.80 | MEN1 (0.68) | CA9ALDH1A1MAPTMEN1KMT2A | |
| Bromide SCHEMBL11180829 | 0.79 | MEN1 (0.66) | CA9ALDH1A1MAPTMEN1KMT2A | |
| Bromide SCHEMBL11277318 | 0.79 | MEN1 (0.66) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL3887727 | 0.78 | ALDH1A1 (0.42) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11996378 | 0.78 | ALDH1A1 (0.42) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11996376 | 0.78 | ALDH1A1 (0.42) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11996377 | 0.78 | ALDH1A1 (0.42) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28177739 | 0.77 | CA9 (0.56) | CA9ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL12013236 | 0.75 | GFER (0.68) | CA9ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031576-A | N-substituted thiazole heterocyclic compound and application thereof | 国科大杭州高等研究院 | 2022-02-11 | — | — | CN | claimed |
| CN-114031576-A | N-substituted thiazole heterocyclic compound and application thereof | 国科大杭州高等研究院 | 2022-02-11 | — | — | CN | disclosed |