Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28683405 | 0.92 | MAPT (0.55) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL28693182 | 0.91 | TP53 (0.52) | ALDH1A1SCN9AMAPTHSD17B10TP53 | |
| SCHEMBL28703717 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL28696462 | 0.80 | ALDH1A1 (0.59) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL29044128 | 0.77 | MAPT (0.59) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL4731713 | 0.76 | SCN9A (0.67) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL28705162 | 0.75 | TP53 (0.55) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL29044119 | 0.74 | MAPT (0.59) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL29044113 | 0.73 | MAPT (0.57) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 | |
| SCHEMBL28693188 | 0.72 | ALDH1A1 (0.77) | ALDH1A1SCN9ANPSR1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057626-A | Indole-2, 3-dione derivative, preparation method thereof and anti-liver cancer drug for inhibiting RECQL4 specific expression | 山东第一医科大学(山东省医学科学院) | 2022-02-18 | — | — | CN | disclosed |