Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28704274 | 0.90 | — | — | |
| SCHEMBL22831979 | 0.83 | BRAF (0.34) | BRAFHCAR3 | |
| SCHEMBL22831947 | 0.74 | BRAF (0.33) | BRAF | |
| SCHEMBL22831977 | 0.72 | BRAF (0.41) | BRAFHCAR3 | |
| SCHEMBL28691715 | 0.67 | BRAF (0.30) | BRAF | |
| SCHEMBL22831945 | 0.64 | BRAF (0.39) | BRAF | |
| SCHEMBL31150404 | 0.64 | BRAF (0.45) | BRAF | |
| SCHEMBL30396199 | 0.63 | KMT2A (0.39) | — | |
| SCHEMBL22831802 | 0.62 | BRAF (0.33) | BRAF | |
| SCHEMBL22832025 | 0.62 | HSPB1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026073-A | Quinazolin-4-one derivatives for the treatment of BRAF related diseases and disorders | ARRAY生物制药公司 | 2022-02-08 | — | — | CN | disclosed |