Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPOX | P50336 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353744 | 0.89 | TDP1 (0.41) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL29021864 | 0.89 | TDP1 (0.41) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL29561773 | 0.87 | LMNA (0.36) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL22832028 | 0.87 | LMNA (0.36) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL30353742 | 0.83 | TDP1 (0.42) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL29021770 | 0.83 | TDP1 (0.42) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL29021594 | 0.82 | TDP1 (0.41) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL30353743 | 0.82 | TDP1 (0.41) | KMT2ATDP1MEN1TTRALB | |
| SCHEMBL29932364 | 0.80 | TDP1 (0.34) | KMT2ATDP1MEN1TTRL3MBTL1 | |
| SCHEMBL29021814 | 0.80 | TDP1 (0.34) | KMT2ATDP1MEN1TTRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096710-A | 4-oxo-3, 4-dihydroquinazolinone compounds for the treatment of BRAF related diseases and disorders | 阿雷生物药品公司 | 2023-05-09 | — | — | CN | disclosed |