Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 9/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ACE | P12821 | 3/20 | 0.60 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.58 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.58 |
| ▸ | ITGAL | P20701 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ECE1 | P42892 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400092 | 1.00 | NMBR (0.62) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL28706022 | 1.00 | NMBR (0.62) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL12017029 | 0.87 | NMBR (0.64) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL29402851 | 0.86 | NMBR (0.56) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL28700214 | 0.86 | NMBR (0.56) | NMBRTACR1GAAMAPTHTT | |
| SCHEMBL8785114 | 0.86 | KCNA5 (0.63) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL4612012 | 0.86 | KCNA5 (0.63) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL3820631 | 0.86 | KCNA5 (0.63) | NMBRALOX15ACEITGB2ICAM1 | |
| SCHEMBL11370921 | 0.85 | ALOX15 (0.67) | ALOX15ACEITGB2ICAM1ITGAL | |
| SCHEMBL11370918 | 0.85 | ALOX15 (0.67) | ALOX15ACEITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114080395-A | Synthesis method of alpha-amanitine and derivatives thereof | 纯生物有机有限公司 | 2022-02-22 | — | — | CN | disclosed |