⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538735 | 1.00 | ALDH1A1 (0.33) | — | |
| SCHEMBL3548852 | 1.00 | ALDH1A1 (0.33) | — | |
| SCHEMBL78895 | 1.00 | — | — | |
| SCHEMBL3546520 | 1.00 | ALDH1A1 (0.33) | — | |
| SCHEMBL20425 | 0.97 | — | — | |
| SCHEMBL3627 | 0.86 | — | — | |
| SCHEMBL1782831 | 0.75 | — | — | |
| SCHEMBL56632 | 0.73 | — | — | |
| SCHEMBL7479667 | 0.69 | — | — | |
| SCHEMBL222337 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7851478-B2 | Agent for preventing and/or treating movement disorder | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-12-14 | — | — | US | disclosed |
| EP-2258372-A1 | A2A antagonists for use in the treatment of motor disorders | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-12-08 | — | — | EP | disclosed |
| US-20090105277-A1 | AGENT FOR PREVENTING AND/OR TREATING MOVEMENT DISORDER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2009-04-23 | — | — | US | disclosed |
| EP-1902716-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR MOTOR DISORDER | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2008-03-26 | — | — | EP | disclosed |
| US-20070185168-A1 | Piperidine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-08-09 | — | — | US | disclosed |
| US-20070149555-A1 | Prophylatic and/or therapeutic agents for chronic musculoskeletal pain | KYOWA HAKKO KOGYO CO., LTD (JP) | 2007-06-28 | — | — | US | disclosed |
| EP-1738766-A1 | PREVENTIVE AND/OR THERAPEUTIC AGENT FOR DISEASE ACCOMPANIED BY CHRONIC MUSCLE/SKELETON PAIN | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2007-01-03 | — | — | EP | disclosed |
| EP-1736474-A1 | PIPERIDINE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-12-27 | — | — | EP | disclosed |