SCHEMBL3627

SCHEMBL3627

C1C[N]NC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20425 0.89
SCHEMBL3538735 0.86 ALDH1A1 (0.33)
SCHEMBL78895 0.86
SCHEMBL3546520 0.86 ALDH1A1 (0.33)
SCHEMBL2870640 0.86
SCHEMBL3548852 0.86 ALDH1A1 (0.33)
SCHEMBL56632 0.78
SCHEMBL3065761 0.65
SCHEMBL4443117 0.65
SCHEMBL5854868 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 109547 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151425-A1 COMPOUNDS AND METHOD FOR TREATING HIV INFECTION THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2024-07-18 WO claimed
CN-118344325-A PI3K selective inhibitors 轩竹生物科技股份有限公司 2024-07-16 CN claimed
US-20240228501-A1 IMIDAZOLE-CONTAINING CONDENSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN MEDICINE CHANGCHUN GENESCIENCE PHARMACEUTICAL CO., LTD. (CN) 2024-07-11 US claimed
US-20240228497-A1 Pyrrolo[2, 3-b]Pyrazine-Based Bifunctional Compounds as HPK1 Degraders and the Use Thereof BEIGENE, LTD. (KY) 2024-07-11 US claimed
US-20240226132-A1 RNA COMPOSITIONS COMPRISING A BUFFER SUBSTANCE AND METHODS FOR PREPARING, STORING AND USING THE SAME BIONTECH DELIVERY TECHNOLOGIES GMBH (DE) 2024-07-11 US claimed
CN-118307518-A Polycyclic PARP selective inhibitors 轩竹生物科技股份有限公司 2024-07-09 CN claimed
CN-113493441-B Novel spiro compound and application thereof in medicines 广东东阳光药业股份有限公司 2024-07-09 CN claimed
CN-118302425-A IRAK4 inhibitors and uses thereof 武汉人福创新药物研发中心有限公司 2024-07-05 CN claimed
WO-2024141011-A1 COMPLEMENT FACTOR B INHIBITOR, PHARMACEUTICAL COMPOSITION AND USE THEREOF 深圳晶泰科技有限公司 2024-07-04 WO claimed
WO-2024140637-A1 OXOISOINDOLINYL SUBSTITUTED PIPERIDINEDIONE DERIVATIVE AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-07-04 WO claimed
EP-0051514-A1 Cinnamoyl-cinnamic acid derivative, its preparation and its use as a therapeutic agent SOCIETE DE RECHERCHES INDUSTRIELLES S.O.R.I. Société anonyme dite: (FR) 1982-05-12 EP claimed
US-4308269-A ANTITUMOUR AGENTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1981-12-29 US claimed
US-4247550-A Compositions and methods for the treatment of hypertension or oedemas LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1981-01-27 US claimed
US-4246409-A ANTIDIARRHEAL AGENTS WILLIAM H. RORER, INC. (US) 1981-01-20 US claimed
EP-0021173-A1 Maytansinoids, their production and use Takeda Chemical Industries, Ltd. (JP) 1981-01-07 EP claimed
US-4213898-A FOR POLYACRYLONITRILE SANDOZ LTD. (CH) 1980-07-22 US claimed
US-4153460-A Light-sensitive silver halide color photographic material KONISHIROKU PHOTO INDUSTRY CO., LTD (JP) 1979-05-08 US claimed
EP-0000299-A1 Novel derivatives of substituted 2-benzoyl-4-chloro-glycinanilides, their preparation and their use as medicines. PIERRE FABRE S.A. (FR) 1979-01-10 EP claimed
US-4113867-A ANTHELMINTICS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1978-09-12 US claimed
US-4108994-A 5-THIAZOLE-METHANE-AMINES, AND THEIR USE AS ANTILIPOLYTICS ROUSSEL UCLAF (FR) 1978-08-22 US claimed