Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.63 |
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25779970 | 0.79 | LMNA (0.69) | LMNATP53THRBMAPTPOLB | |
| SCHEMBL25780872 | 0.79 | LMNA (0.73) | LMNATP53THRBMAPTPOLB | |
| SCHEMBL7241937 | 0.77 | AVPR2 (0.68) | — | |
| SCHEMBL2332195 | 0.76 | RAB9A (0.88) | — | |
| SCHEMBL25294241 | 0.76 | IDO1 (0.66) | LMNATP53MAPT | |
| SCHEMBL28715770 | 0.76 | IDO1 (0.66) | LMNATP53MAPT | |
| SCHEMBL19689659 | 0.75 | MAPT (0.88) | LMNATP53MAPTPOLB | |
| SCHEMBL5784422 | 0.75 | TP53 (0.63) | LMNATP53THRBMAPTPOLB | |
| SCHEMBL9549034 | 0.75 | TP53 (0.63) | LMNATP53MAPTPOLB | |
| SCHEMBL25779972 | 0.74 | LMNA (0.66) | LMNATP53THRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213310-B | Indoline compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-23 | — | — | CN | claimed |
| CN-114213310-A | Indoline compound and derivative, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2022-03-22 | — | — | CN | claimed |
| CN-114213310-B | Indoline compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2024-02-23 | — | — | CN | disclosed |
| CN-114213310-A | Indoline compound and derivative, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2022-03-22 | — | — | CN | disclosed |