Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.32 |
| ▸ | ATR | Q13535 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792137 | 0.89 | PDE10A (0.39) | DGAT2PDE10ACYP4F2CYP4A11KDR | |
| SCHEMBL28698688 | 0.89 | PDE10A (0.39) | DGAT2PDE10ACYP4F2CYP4A11KDR | |
| SCHEMBL29390079 | 0.89 | PDE10A (0.39) | DGAT2PDE10ACYP4F2CYP4A11KDR | |
| SCHEMBL28698692 | 0.89 | PDE10A (0.39) | DGAT2PDE10ACYP4F2CYP4A11KDR | |
| SCHEMBL30792270 | 0.81 | RET (0.37) | CYP4F2CYP4A11KDRATRRET | |
| SCHEMBL28684894 | 0.81 | RET (0.37) | CYP4F2CYP4A11KDRATRRET | |
| SCHEMBL28684897 | 0.81 | RET (0.37) | CYP4F2CYP4A11KDRATRRET | |
| SCHEMBL29387740 | 0.81 | RET (0.37) | CYP4F2CYP4A11KDRATRRET | |
| SCHEMBL29705188 | 0.81 | FGFR1 (0.38) | PDE10ACYP4F2CYP4A11ATRRET | |
| SCHEMBL18198891 | 0.81 | FGFR1 (0.38) | PDE10ACYP4F2CYP4A11ATRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |