Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.35 |
| ▸ | ATR | Q13535 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792137 | 1.00 | PDE10A (0.39) | PDE10AHCAR3HSD17B10GAARXRA | |
| SCHEMBL29390079 | 1.00 | PDE10A (0.39) | PDE10AHCAR3HSD17B10GAARXRA | |
| SCHEMBL28698688 | 1.00 | PDE10A (0.39) | PDE10AHCAR3HSD17B10GAARXRA | |
| SCHEMBL28707121 | 0.89 | DGAT2 (0.34) | PDE10ARXRARXRBRXRGDGAT2 | |
| SCHEMBL30792270 | 0.86 | RET (0.37) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL28684894 | 0.86 | RET (0.37) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL28684897 | 0.86 | RET (0.37) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL29387740 | 0.86 | RET (0.37) | RXRARXRBRXRGCYP4F2CYP4A11 | |
| SCHEMBL29705188 | 0.86 | FGFR1 (0.38) | PDE10ACYP4F2CYP4A11ATRMEN1 | |
| SCHEMBL18198891 | 0.86 | FGFR1 (0.38) | PDE10ACYP4F2CYP4A11ATRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |