Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.76 |
| ▸ | AMY1A | P0DUB6 | 9/20 | 0.64 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.58 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | VCP | P55072 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525682 | 0.88 | KDM1A (0.76) | KDM1AAMY1ATRPC3TRPC6ALDH1A1 | |
| SCHEMBL28717687 | 0.84 | KDM1A (0.67) | KDM1AAMY1ATRPC3TRPC6ALDH1A1 | |
| SCHEMBL28712067 | 0.84 | KDM1A (0.57) | KDM1AAMY1ATRPC3TRPC6MAPT | |
| SCHEMBL27827106 | 0.84 | AMY1A (0.63) | KDM1AAMY1AMEN1MAPTKMT2A | |
| SCHEMBL6107121 | 0.82 | KDM1A (0.53) | KDM1AAMY1ATRPC3TRPC6MAPT | |
| SCHEMBL29654005 | 0.82 | KDM1A (0.78) | KDM1AAMY1AALDH1A1MEN1MAPT | |
| SCHEMBL28707161 | 0.82 | KDM1A (0.78) | KDM1AAMY1AALDH1A1MEN1MAPT | |
| SCHEMBL27827048 | 0.81 | AMY1A (0.67) | KDM1AAMY1ATRPC3TRPC6MEN1 | |
| SCHEMBL5041112 | 0.79 | EGFR (0.73) | KDM1AALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL772481 | 0.78 | KDM1A (0.66) | KDM1AAMY1ATRPC3TRPC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114249702-B | N-aryl- [2,4 '-dithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114249702-A | N-aryl- [2,4 '-bithiazole ] -2' -amine compound and preparation and application thereof | 沈阳药科大学 | 2022-03-29 | — | — | CN | disclosed |