Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.44 |
| ▸ | MET | P08581 | 5/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | WNT1 | P04628 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28935935 | 0.87 | PIK3CD (0.40) | PIK3CAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL28701717 | 0.87 | PIK3CD (0.40) | METPIK3CAKDM4ENPC1ALDH1A1 | |
| SCHEMBL28714673 | 0.86 | GRK5 (0.49) | PIM1PIM2METPIK3CAPIK3CD | |
| SCHEMBL28935891 | 0.85 | HSPD1 (0.38) | METPIK3CAKDM4ENPC1ALDH1A1 | |
| SCHEMBL31165937 | 0.84 | GRK5 (0.44) | PIM1PIM2METALKGRK5 | |
| SCHEMBL23033561 | 0.83 | PIM1 (0.55) | PIM1PIM2METCCNCCDK8 | |
| SCHEMBL28713414 | 0.83 | NPC1 (0.39) | PIK3CAKDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL17820257 | 0.82 | ERN1 (0.46) | PIM1PIM2ALKPIK3CAACVR1 | |
| SCHEMBL28935931 | 0.82 | UTRN (0.37) | PIK3CAWNT1DYRK1AKDM4ENPC1 | |
| SCHEMBL28714666 | 0.82 | NPC1 (0.38) | PIK3CAKDM4ENPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114269725-B | Anti-influenza virus compound, preparation method and application thereof | 西藏海思科制药有限公司 | 2024-09-17 | — | — | CN | disclosed |
| CN-114269725-A | Anti-influenza virus compound and preparation method and application thereof | 四川海思科制药有限公司 | 2022-04-01 | — | — | CN | disclosed |