Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL980115 | 0.87 | ALDH1A1 (0.63) | KMT2AMEN1P2RX7LMNACYP1A2 | |
| SCHEMBL15819777 | 0.86 | TDP1 (0.52) | KMT2AMEN1P2RX7CYP1A2CYP2C9 | |
| SCHEMBL1248162 | 0.80 | P2RX7 (0.66) | P2RX7LMNAALDH1A1HTTTDP1 | |
| SCHEMBL27819878 | 0.80 | P2RX7 (0.66) | P2RX7LMNAALDH1A1HTTTDP1 | |
| Methyl Alcohol SCHEMBL27938435 | 0.78 | P2RX7 (0.64) | P2RX7LMNAALDH1A1HTTTDP1 | |
| SCHEMBL19191513 | 0.77 | MAPT (0.63) | KMT2AMEN1SMN1; SMN2LMNAMAPT | |
| SCHEMBL28760397 | 0.77 | P2RX7 (0.50) | KMT2AMEN1SMN1; SMN2P2RX7LMNA | |
| Iodide SCHEMBL19357606 | 0.76 | P2RX7 (0.61) | KMT2ASMN1; SMN2P2RX7LMNAMAPT | |
| SCHEMBL23830170 | 0.75 | P2RX7 (0.59) | KMT2ASMN1; SMN2P2RX7LMNAMAPT | |
| SCHEMBL16118581 | 0.75 | P2RX7 (0.64) | SMN1; SMN2P2RX7LMNAMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884047-B | Intermediates for the synthesis of aryl or heteroaryl substituted 5-hydroxy-1, 7-naphthyridine compounds and methods for their preparation | 沈阳三生制药有限责任公司 | 2022-03-08 | — | — | CN | disclosed |