SCHEMBL28707653

SCHEMBL28707653

Oc1ccccc1N=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL574042 0.77 MAPT (1.00)
SCHEMBL29354111 0.77 MAPT (1.00)
SCHEMBL304890 0.77 MAPT (0.68)
SCHEMBL131175 0.77 MAPT (1.00)
SCHEMBL29710671 0.74 MAPT (0.94)
SCHEMBL27424712 0.74 MAPT (0.94)
SCHEMBL625151 0.74 MAPT (0.94)
SCHEMBL27424715 0.74 MAPT (0.94)
SCHEMBL6707273 0.74 MAPT (0.94)
SCHEMBL3774226 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115340581-B Synthesis method and application of o-phenol sulfenamide on-DNA compound 深圳市小分子新药创新中心有限公司 2023-02-03 CN disclosed
CN-115340581-A Synthesis method and application of o-phenol sulfenamide on-DNA compound 深圳市小分子新药创新中心有限公司 2022-11-15 CN disclosed
CN-113980077-B Synthesis method and application of on-DNA (deoxyribonucleic acid) o-phenol sulfilimine compound 深圳市小分子新药创新中心有限公司 2022-05-17 CN disclosed
CN-113980077-A Synthesis method and application of on-DNA (deoxyribonucleic acid) o-phenol sulfilimine compound 深圳市小分子新药创新中心有限公司 2022-01-28 CN disclosed