SCHEMBL304890

SCHEMBL304890

Oc1ccccc1[N]c1ccccc1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.68
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
NPC1 O15118 5/20 0.68
LMNA P02545 5/20 0.68
KDM4E B2RXH2 5/20 0.68
HTT P42858 4/20 0.68
ALDH1A1 P00352 6/20 0.53
CA2 P00918 4/20 0.53
POLB P06746 3/20 0.53
RAB9A P51151 3/20 0.53
HSD17B10 Q99714 3/20 0.53
ALOX15 P16050 3/20 0.53
HPGD P15428 3/20 0.53
CA12 O43570 2/20 0.53
EGFR P00533 2/20 0.53
FYN P06241 2/20 0.53
MMP9 P14780 2/20 0.53
RECQL P46063 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL131175 0.81 MAPT (1.00) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29354111 0.81 MAPT (1.00) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL574042 0.81 MAPT (1.00) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL27424712 0.79 MAPT (0.94) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL29710671 0.79 MAPT (0.94) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL625151 0.79 MAPT (0.94) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL27424715 0.79 MAPT (0.94) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL6707273 0.79 MAPT (0.94) MAPTMEN1KMT2ASMN1; SMN2NPC1
SCHEMBL431918 0.77
SCHEMBL1560140 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2616513-B1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECH CO (SA) 2019-11-06 EP claimed
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. 2018-06-28 US claimed
US-20160137777-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2016-05-19 US claimed
US-9284406-B2 Catalysts and methods for polymer synthesis NOVOMER, INC. (US) 2016-03-15 US claimed
EP-2616513-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS Novomer, Inc. (US) 2013-07-24 EP claimed
US-20130172524-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2013-07-04 US claimed
WO-2012037282-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2012-03-22 WO claimed
JP-2012500867-A 2012-01-12 JP claimed
EP-2321364-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS Novomer, Inc. (US) 2011-05-18 EP claimed
WO-2010022388-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2010-02-25 WO claimed
EP-3486269-B1 POLYMERIZATION SYSTEM FOR THE COPOLYMERIZATION OF CO2 AND EPOXIDES AND RELATED METHOD SAUDI ARAMCO TECH CO (SA) 2023-12-20 EP disclosed
EP-2337809-B2 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS SAUDI ARAMCO TECH CO (SA) 2023-11-29 EP disclosed
EP-2794719-B1 METHODS FOR POLYMER SYNTHESIS SAUDI ARAMCO TECH CO (SA) 2023-08-23 EP disclosed
US-11566105-B2 Semi-batch process for making polycarbonate polyols via copolymerization of carbon dioxide and an oxirane DOW GLOBAL TECHNOLOGIES LLC (US) 2023-01-31 US disclosed
US-11535706-B2 Polycarbonate polyol compositions and methods SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) 2022-12-27 US disclosed
EP-2337809-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc. (US) 2011-06-29 EP disclosed
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2011-06-23 US disclosed
EP-2321364-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS Novomer, Inc. (US) 2011-05-18 EP disclosed
WO-2010028362-A1 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2010-03-11 WO disclosed
WO-2010022388-A2 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS NOVOMER, INC. (US) 2010-02-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180179242-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 MAPT 3940/4885MEN1 3240/4885KMT2A 1825/4885
US-20110152497-A1 CATALYSTS AND METHODS FOR POLYMER SYNTHESIS PPOX, COASY, SOD1 MAPT 3940/4885MEN1 3240/4885KMT2A 1825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.