SCHEMBL28707993

SCHEMBL28707993

Cc1cc(C2CCCCC2)c2cc(C(F)(F)F)ccc2n1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAK O14976 1/20 0.44
PTGDR2 Q9Y5Y4 1/20 0.43
MCHR1 Q99705 1/20 0.39
CCNE2 O96020 1/20 0.39
CCNA2 P20248 1/20 0.39
CCNE1 P24864 1/20 0.39
CDK2 P24941 1/20 0.39
CCNA1 P78396 1/20 0.39
CSNK1D P48730 1/20 0.39
ATM Q13315 1/20 0.39
PSMB5 P28074 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28937451 0.88 PSMB5 (0.39) ATMPSMB5
SCHEMBL28729113 0.82 ATM (0.55) PTGDR2ATMPSMB5
SCHEMBL28714760 0.81 LMNA (0.50) PTGDR2ATMPSMB5
SCHEMBL21834809 0.77 CYP1A2 (0.51) ATMPSMB5
SCHEMBL28708579 0.77 CYP1A2 (0.51) ATMPSMB5
SCHEMBL30524345 0.77 CAMKK1 (0.46) PSMB5
SCHEMBL28709641 0.77 CAMKK1 (0.46) PSMB5
SCHEMBL28708591 0.75 CYP1A2 (0.53) ATMPSMB5
SCHEMBL28708581 0.75 LMNA (0.43) PTGDR2ATMPSMB5
SCHEMBL28723048 0.75 NCF1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114277389-B Method for synthesizing quinoline derivative by utilizing pyridinium photoelectrocatalysis Minisci reaction 齐鲁工业大学 2023-09-19 CN disclosed
CN-114277389-A Method for synthesizing quinoline derivative by utilizing pyridinium photoelectrocatalysis Minisci reaction 齐鲁工业大学 2022-04-05 CN disclosed