SCHEMBL28708012

SCHEMBL28708012

CCOC(=O)C(C)(C)CCc1ccc(CCCCC(C)(C)C(=O)O)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 2/20 0.51
CYP4A11 Q02928 2/20 0.51
LTB4R Q15722 5/20 0.46
PPARA Q07869 6/20 0.41
PPARG P37231 2/20 0.41
TTR P02766 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C8 P10632 1/20 0.40
CHRM1 P11229 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
ADRA1A P35348 1/20 0.40
HTR2B P41595 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SLCO1B3 Q9NPD5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CISD1 Q9NZ45 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MMP8 P22894 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22922062 0.91 CYP4F2 (0.60) CYP4F2CYP4A11LTB4RPPARAPPARG
SCHEMBL22922179 0.87 CYP4F2 (0.57) CYP4F2CYP4A11PPARAPPARGCYP1A2
SCHEMBL31001663 0.87 CYP4F2 (0.51) CYP4F2CYP4A11PPARAPPARGCYP1A2
SCHEMBL22921268 0.83 LTB4R (0.57) LTB4RPPARAPPARGTTRCYP1A2
SCHEMBL11860437 0.82 CYP4F2 (0.53) CYP4F2CYP4A11LTB4RPPARAPPARG
SCHEMBL15419571 0.82 MMP8 (0.54) CYP4F2CYP4A11PPARAPPARGSMN1; SMN2
SCHEMBL22921399 0.82 LTB4R (0.59) LTB4RPPARAPPARGTTRCYP1A2
SCHEMBL22921467 0.82 LTB4R (0.59) LTB4RPPARAPPARGTTRCYP1A2
SCHEMBL22921307 0.82 LTB4R (0.59) LTB4RPPARAPPARGTTRCYP1A2
SCHEMBL28709282 0.81 CYP4F2 (0.52) CYP4F2CYP4A11LTB4RPPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114126593-A Functionalized long chain hydrocarbon mono-and dicarboxylic acids useful for preventing or treating disease 埃斯佩尔维塔治疗股份有限公司 2022-03-01 CN disclosed