Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSPB1 | P04792 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2531644 | 0.89 | HSPB1 (0.57) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL30970189 | 0.89 | MAPT (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL13548695 | 0.88 | MAPT (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL18345260 | 0.82 | HSPB1 (0.46) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL2538774 | 0.82 | TSHR (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL311393 | 0.81 | MEN1 (0.60) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL443483 | 0.81 | HSD17B10 (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL30072571 | 0.81 | HSD17B10 (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL6180876 | 0.81 | MERTK (0.52) | MEN1KMT2AL3MBTL1POLBMAPT | |
| SCHEMBL30317903 | 0.81 | ALDH1A1 (0.48) | MEN1KMT2AL3MBTL1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072387-B | Indazole compound, pharmaceutical composition and application thereof | 暨南大学 | 2024-03-08 | — | — | CN | disclosed |
| CN-114072387-A | Indazole compound and medicinal composition and application thereof | 暨南大学 | 2022-02-18 | — | — | CN | disclosed |