SCHEMBL2870858

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2861016	0.80	ITK (0.68)	ITKAURKAMAPKAPK2KMT2A
	SCHEMBL2869945	0.78	TTK (0.67)	ITKAURKAMAPKAPK2MEN1KMT2A
	SCHEMBL2862749	0.78	MAPKAPK2 (0.50)	ITKAURKAMAPKAPK2
	SCHEMBL2862144	0.78	MAPKAPK2 (0.50)	ITKAURKAMAPKAPK2
	SCHEMBL2868361	0.78	AURKA (0.50)	ITKAURKAMAPKAPK2MEN1KMT2A
	SCHEMBL8251866	0.78	JAK2 (0.74)	ITKAURKALRRK2JAK2JAK1
	SCHEMBL2864712	0.77	ITK (0.56)	ITKAURKAMAPKAPK2MEN1KMT2A
	SCHEMBL5379148	0.77	JAK2 (0.65)	ITKAURKALRRK2JAK2JAK1
	SCHEMBL2859260	0.77	TTK (0.51)	ITKAURKAMAPKAPK2
	SCHEMBL2871320	0.77	PDPK1 (0.66)	ITKMAPKAPK2PDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.