SCHEMBL2861016

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2864712	0.87	ITK (0.56)	ITKTTKMAPKAPK2KDM4EKMT2A
	SCHEMBL8260089	0.86	TTK (0.69)	ITKTTKMAPK8KDM4EMTNR1A
	SCHEMBL2871320	0.84	PDPK1 (0.66)	ITKMAPKAPK2
	SCHEMBL2862749	0.83	MAPKAPK2 (0.50)	ITKTTKMAPK8MAPKAPK2AURKA
	SCHEMBL2862144	0.83	MAPKAPK2 (0.50)	ITKTTKMAPK8MAPKAPK2AURKA
	SCHEMBL2867415	0.81	ULK1 (0.64)	ITKMAPKAPK2
	SCHEMBL2869945	0.81	TTK (0.67)	ITKTTKMAPKAPK2KDM4EKMT2A
	SCHEMBL2866378	0.81	ITK (0.59)	ITKTTKMAPKAPK2AURKA
	SCHEMBL2868361	0.80	AURKA (0.50)	ITKTTKMAPKAPK2KMT2AAURKA
	SCHEMBL2870858	0.80	ITK (0.57)	ITKMAPKAPK2KMT2AAURKA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.