SCHEMBL2862749

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2862144	0.92	MAPKAPK2 (0.50)	MAPKAPK2ITKAURKATTKMAPK8
	SCHEMBL2861016	0.83	ITK (0.68)	MAPKAPK2ITKAURKATTKMAPK8
	SCHEMBL2864712	0.80	ITK (0.56)	MAPKAPK2ITKAURKATTK
	SCHEMBL2870858	0.78	ITK (0.57)	MAPKAPK2ITKAURKA
	SCHEMBL2868361	0.78	AURKA (0.50)	MAPKAPK2ITKAURKATTK
	SCHEMBL2871320	0.78	PDPK1 (0.66)	MAPKAPK2ITK
	SCHEMBL2859260	0.76	TTK (0.51)	MAPKAPK2ITKAURKATTK
	SCHEMBL2869945	0.75	TTK (0.67)	MAPKAPK2ITKAURKATTK
	SCHEMBL2867415	0.75	ULK1 (0.64)	MAPKAPK2ITK
	SCHEMBL2866378	0.74	ITK (0.59)	MAPKAPK2ITKAURKATTK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.