SCHEMBL28709160

SCHEMBL28709160

O=C(Nc1ccnc(=O)[nH]1)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
KCNH2 Q12809 1/20 0.56
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
MAPT P10636 1/20 0.55
CTDSP1 Q9GZU7 1/20 0.55
LMNA P02545 1/20 0.48
JAK2 O60674 1/20 0.47
TYK2 P29597 1/20 0.47
BCAT2 O15382 2/20 0.47
KCNK3 O14649 1/20 0.47
KCNK9 Q9NPC2 1/20 0.47
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
PABPC1 P11940 1/20 0.46
CCR6 P51684 1/20 0.46
ATM Q13315 1/20 0.46
HKDC1 Q2TB90 1/20 0.46
AURKA O14965 1/20 0.46
MAPK13 O15264 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL655272 0.76 KCNH2 (0.51) POLBKCNH2NPC1RAB9AMAPT
SCHEMBL4760376 0.75 SIRT2 (0.62) NPC1RAB9AJAK2TYK2BCAT2
SCHEMBL2463454 0.73 POLB (0.47) POLBKCNH2NPC1RAB9AMAPT
SCHEMBL16735682 0.71 MDM4 (0.51) POLBNPC1RAB9ABCAT2KCNK3
SCHEMBL27811120 0.71 PTPN1 (0.46) POLBNPC1RAB9AMAPTBCAT2
N4-Hydroxycytosine SCHEMBL31006505 0.71
SCHEMBL2427655 0.70 JAK2 (0.50) POLBNPC1RAB9AMAPTJAK2
SCHEMBL997872 0.70 RAB9A (0.59) NPC1RAB9AJAK2TYK2KCNK3
SCHEMBL29238957 0.68 RAB9A (0.57) NPC1RAB9AJAK2TYK2KCNK3
SCHEMBL11002565 0.68 MEN1 (0.50) POLBNPC1RAB9AMAPTKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
EP-4286519-A2 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORPORATION (US) 2023-12-06 EP disclosed
CN-114014902-B Dimeric nucleotide and synthesis method thereof 上海兆维科技发展有限公司 2023-12-01 CN disclosed
EP-3137479-B1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF MAKING THE SAME GERON CORP (US) 2023-08-30 EP disclosed
EP-3980554-A1 HYBRIDIZING ALL-LNA OLIGONUCLEOTIDES F. Hoffmann-La Roche AG (CH) 2022-04-13 EP disclosed
CN-114014902-A Dimeric nucleotide and synthetic method thereof 上海兆维科技发展有限公司 2022-02-08 CN disclosed