Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 6/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 6/20 | 0.44 |
| ▸ | ITGB8 | P26012 | 6/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 5/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 5/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.44 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.44 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709399 | 0.91 | SMYD3 (0.41) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28698405 | 0.91 | SMYD3 (0.41) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28709231 | 0.89 | SMYD3 (0.40) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28709233 | 0.89 | SMYD3 (0.40) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28699688 | 0.76 | ITGAV (0.39) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28984876 | 0.74 | KHK (0.38) | SMYD3RIPK1KHK | |
| SCHEMBL28692102 | 0.73 | L3MBTL1 (0.45) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL28690085 | 0.73 | CYP26A1 (0.40) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL16115886 | 0.72 | L3MBTL1 (0.45) | ITGAVITGB6ITGB8ITGB5ITGB1 | |
| SCHEMBL30898093 | 0.70 | ITGAV (0.50) | ITGAVITGB6ITGB8ITGB5ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354635-A | Pyrrolidine integrin regulator and application thereof | 清药同创(北京)药物研发中心有限公司 | 2021-09-07 | — | — | CN | disclosed |