SCHEMBL28709353

SCHEMBL28709353

CCCCc1ccc(C(=O)OP(=O)(O)O)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 1/20 0.57
RARB P10826 6/20 0.53
THRA P10827 3/20 0.51
THRB P10828 3/20 0.51
TRPV1 Q8NER1 1/20 0.50
S1PR1 P21453 1/20 0.49
S1PR3 Q99500 1/20 0.49
CYP4A11 Q02928 2/20 0.49
ENPP2 Q13822 1/20 0.49
ALDH1A1 P00352 2/20 0.49
HPGD P15428 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP4F2 P78329 1/20 0.47
MEN1 O00255 1/20 0.46
RARA P10276 1/20 0.46
MAPT P10636 1/20 0.46
MTOR P42345 1/20 0.46
KMT2A Q03164 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29017979 0.90 PLK1 (0.54) PLK1THRBTRPV1S1PR1S1PR3
SCHEMBL29018270 0.84 ALDH1A1 (0.53) PLK1S1PR1S1PR3ALDH1A1HPGD
SCHEMBL28701861 0.84 PLK1 (0.54) PLK1RARBTHRATHRBTRPV1
SCHEMBL7131124 0.81 RARB (0.61) PLK1RARBTHRATHRBTRPV1
SCHEMBL6939507 0.81 RARB (0.61) PLK1RARBTHRATHRBTRPV1
SCHEMBL28695446 0.80 PLK1 (0.46) PLK1RARBTHRATHRBTRPV1
SCHEMBL7560761 0.80 RARB (0.59) PLK1RARBTHRATHRBTRPV1
SCHEMBL1792416 0.80 CYP4A11 (0.74) PLK1RARBTHRATHRBTRPV1
SCHEMBL28931706 0.79 TRPV1 (0.52) PLK1RARBTHRATHRBTRPV1
Phosphoric Acid SCHEMBL28423092 0.78 ENPP2 (0.66) PLK1RARBTHRATHRBTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113929798-B Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2023-07-21 CN claimed
CN-113929797-B Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2023-07-21 CN claimed
CN-113929799-B Catalyst component for olefin polymerization, catalyst system and use 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN claimed
CN-113929798-B Solid catalyst component and catalyst system for olefin polymerization 中国石油化工股份有限公司 2023-07-21 CN disclosed
CN-113929797-B Solid catalyst component and catalyst system for producing polymers 中国石油化工股份有限公司 2023-07-21 CN disclosed
CN-113929799-B Catalyst component for olefin polymerization, catalyst system and use 中国石油化工股份有限公司 2023-05-09 CN disclosed
CN-114085301-B Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2023-05-09 CN disclosed
CN-114085301-A Solid catalyst component for preparing olefin polymer and application thereof 中国石油化工股份有限公司 2022-02-25 CN disclosed