Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8885102 | 0.72 | MTNR1A (0.57) | POLBSMN1; SMN2HDAC1 | |
| SCHEMBL19273894 | 0.71 | FFAR4 (0.53) | FFAR4 | |
| SCHEMBL28309401 | 0.70 | NPC1 (0.57) | LMNASMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL8883232 | 0.70 | EPHX1 (0.52) | KMT2AMEN1RAB9A | |
| SCHEMBL19260442 | 0.69 | FFAR4 (0.51) | FFAR4KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8633497 | 0.68 | ALDH1A1 (0.43) | FFAR4MAPK10KMT2APOLBLMNA | |
| SCHEMBL8884408 | 0.68 | MTNR1A (0.65) | KMT2APOLBHTTLMNASMN1; SMN2 | |
| SCHEMBL27857859 | 0.67 | FFAR4 (0.43) | FFAR4 | |
| SCHEMBL8883839 | 0.67 | MTNR1A (0.57) | KMT2AHTTLMNASMN1; SMN2HPGD | |
| SCHEMBL8884072 | 0.67 | PSMB8 (0.46) | KMT2AHTTLMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071562-B | Fused 1, 4-oxazepine and related analogs as BET bromodomain inhibitors | 密执安大学评议会 | 2022-03-22 | — | — | CN | disclosed |