Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | LDHA | P00338 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48525 | 1.00 | HTT (0.66) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL9262585 | 0.94 | HTT (0.59) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL9417745 | 0.94 | HTT (0.59) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL7149097 | 0.94 | HTT (0.59) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL29111694 | 0.89 | POLB (0.57) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL11346487 | 0.89 | HTT (0.54) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| Propylene Glycol SCHEMBL29111692 | 0.89 | POLB (0.62) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL18327985 | 0.88 | HTT (0.53) | HTTPOLBSMN1; SMN2CTBP2PKM | |
| SCHEMBL12895869 | 0.86 | SMN1; SMN2 (0.57) | HTTPOLBSMN1; SMN2PKMALDH1A1 | |
| Anisole SCHEMBL29180163 | 0.86 | ALDH1A1 (0.58) | HTTSMN1; SMN2ALDH1A1USP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114088855-A | Feces biomarker for early diagnosis of tibial cartilage dysplasia of broiler chicken and application thereof | 河南农业大学 | 2022-02-25 | — | — | CN | disclosed |