Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | STAT1 | P42224 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20187410 | 0.82 | TRPA1 (0.61) | TRPA1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL20187462 | 0.82 | KMT2A (0.56) | TRPA1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL21367675 | 0.80 | TRPA1 (0.58) | TRPA1SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL13799935 | 0.79 | SMN1; SMN2 (0.76) | HDAC6SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL10244909 | 0.79 | PDE4A (0.49) | TRPA1SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL31123004 | 0.79 | PDE4A (0.49) | TRPA1SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL23718300 | 0.78 | TRPA1 (0.48) | TRPA1SMN1; SMN2ALDH1A1LMNARAB9A | |
| SCHEMBL21363424 | 0.78 | TRPA1 (0.47) | TRPA1 | |
| SCHEMBL2697790 | 0.77 | PSMB5 (0.56) | HDAC6SMN1; SMN2KDM4ERAB9ASTAT1 | |
| SCHEMBL28414230 | 0.76 | ACHE (0.54) | TRPA1SMN1; SMN2KDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110225911-B | Oxadiazolone transient receptor potential channel inhibitors | 豪夫迈·罗氏有限公司 | 2022-04-05 | — | — | CN | disclosed |