Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 10/20 | 0.55 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.43 |
| ▸ | CKS1B | P61024 | 1/20 | 0.43 |
| ▸ | SKP1 | P63208 | 1/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29749147 | 0.90 | RET (0.53) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL21564574 | 0.89 | RET (0.45) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL28542249 | 0.89 | RET (0.45) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL28542250 | 0.89 | RET (0.45) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL29891163 | 0.89 | RET (0.45) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL21564571 | 0.89 | RET (0.45) | RETEIF2AK4OPRK1CKS1BSKP1 | |
| SCHEMBL389068 | 0.86 | SYK (0.53) | RETCKS1BSKP1SKP2SYK | |
| SCHEMBL389069 | 0.86 | SYK (0.53) | RETCKS1BSKP1SKP2SYK | |
| SCHEMBL390147 | 0.86 | SYK (0.53) | RETCKS1BSKP1SKP2SYK | |
| SCHEMBL3025692 | 0.84 | CKS1B (0.60) | RETOPRK1CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113461670-B | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-113461670-A | Novel compounds as inhibitors of rearrangement kinase during transfection | 南京天印健华医药科技有限公司 | 2021-10-01 | — | — | CN | disclosed |