Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.56 |
| ▸ | NOS1 | P29475 | 3/20 | 0.56 |
| ▸ | NOS2 | P35228 | 3/20 | 0.56 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28710330 | 1.00 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL2314636 | 0.95 | NOS3 (0.52) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL29429685 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL42647 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL2030783 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL42646 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| Hydrochloric Acid SCHEMBL25215525 | 0.82 | NOS3 (0.55) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL13971424 | 0.82 | SLC7A5 (0.69) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL9164980 | 0.82 | SLC7A5 (0.69) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL23069036 | 0.80 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107405399-B | Bispecific antibodies against plasma kallikrein and factor XII | 武田药品工业株式会社 | 2022-02-08 | — | — | CN | disclosed |