Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.56 |
| ▸ | NOS1 | P29475 | 3/20 | 0.56 |
| ▸ | NOS2 | P35228 | 3/20 | 0.56 |
| ▸ | DPP4 | P27487 | 3/20 | 0.54 |
| ▸ | FAP | Q12884 | 2/20 | 0.54 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.54 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.54 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | XIAP | P98170 | 1/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2030783 | 1.00 | NOS3 (0.56) | NOS3NOS1NOS2DPP4FAP | |
| SCHEMBL42646 | 1.00 | NOS3 (0.56) | NOS3NOS1NOS2DPP4FAP | |
| SCHEMBL42647 | 1.00 | NOS3 (0.56) | NOS3NOS1NOS2DPP4FAP | |
| Hydrochloric Acid SCHEMBL25215525 | 0.98 | NOS3 (0.55) | NOS3NOS1NOS2DPP4FAP | |
| SCHEMBL25718868 | 0.85 | DPP4 (0.53) | NOS3NOS1NOS2DPP4FAP | |
| SCHEMBL28346433 | 0.84 | KMT2A (0.53) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL28710330 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL28710331 | 0.83 | NOS3 (0.56) | NOS3NOS1NOS2SLC7A5PKM | |
| SCHEMBL7382769 | 0.83 | CYP1A2 (0.50) | DPP4FAPDPP8DPP9DPP7 | |
| SCHEMBL10067850 | 0.82 | NOS3 (0.49) | NOS3NOS1NOS2DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025128649-A1 | A TRANSLATION-INDEPENDENT DIRECTED EVOLUTION STRATEGY TO ENGINEER AMINOACYL-TRNA SYNTHETASES | TRUSTEES OF BOSTON COLLEGE (US) | 2025-06-19 | — | — | WO | claimed |
| US-20260116855-A1 | ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS | PALATIN TECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | disclosed |
| US-20260083852-A1 | PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR | UNIV CALIFORNIA (US) | 2026-03-26 | — | — | US | disclosed |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | NEW YORK UNIVERSITY (US) | 2026-01-01 | — | — | US | disclosed |
| US-12485182-B2 | Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-02 | — | — | US | disclosed |
| US-12459894-B2 | Orally active melanocortin receptor-4 compounds | PALATIN TECHNOLOGIES, INC. (US) | 2025-11-04 | — | — | US | disclosed |
| US-20250327074-A1 | THE RARE CODON RECODING PLATFORM FOR NONCANONICAL AMINO ACIDS INCORPORATION IN MAMMALIAN CELLS | SHAOXING INSTITUTE, ZHEJIANG UNIVERSITY (CN) | 2025-10-23 | — | — | US | disclosed |
| US-12384813-B2 | Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates | MIRECA MEDICINES GMBH (DE) | 2025-08-12 | — | — | US | disclosed |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | NEW YORK UNIVERSITY (US) | 2025-07-29 | — | — | US | disclosed |
| WO-2025128649-A1 | A TRANSLATION-INDEPENDENT DIRECTED EVOLUTION STRATEGY TO ENGINEER AMINOACYL-TRNA SYNTHETASES | TRUSTEES OF BOSTON COLLEGE (US) | 2025-06-19 | — | — | WO | disclosed |
| EP-4021941-A1 | A SINGLE-DOMAIN ANTIBODY FOR TARGETING PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) | National Institute for Biotechnology in the Negev Ltd. (IL) | 2022-07-06 | — | — | EP | disclosed |
| US-20220204450-A1 | Orally Active Melanocortin Receptor-4 Compounds | PALATIN TECHNOLOGIES, INC. (US) | 2022-06-30 | — | — | US | disclosed |
| EP-4013440-A1 | THERAPEUTIC PEPTIDES | Cohbar Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| US-11332497-B2 | Therapeutic peptides | COHBAR, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3983543-A1 | REAGENTS AND METHODS FOR REPLICATION, TRANSCRIPTION, AND TRANSLATION IN SEMI-SYNTHETIC ORGANISMS | The Scripps Research Institute (US) | 2022-04-20 | — | — | EP | disclosed |
| WO-2022076334-A2 | CLEANING COMPOSITION COMPRISING AN ALPHA-DIOXYGENASE | THE PROCTER & GAMBLE COMPANY (US) | 2022-04-14 | — | — | WO | disclosed |
| EP-3976635-A1 | METHODS OF TREATING HYPERLIPIDEMIA CONDITIONS WITH NETRIN-1 COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-04-06 | — | — | EP | disclosed |
| CN-114269367-A | Therapeutic peptides | 科巴公司 | 2022-04-01 | — | — | CN | disclosed |
| WO-2022066534-A1 | ENGINEERED BIOCATALYSTS AND METHODS FOR SYNTHESIZING CHIRAL AMINES | CODEXIS, INC. (US) | 2022-03-31 | — | — | WO | disclosed |
| EP-3966223-A1 | PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF | The Feinstein Institutes for Medical Research (US) | 2022-03-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12459894-B2 | Orally active melanocortin receptor-4 compounds | MC4R, MC1R, MC3R | NOS3 3583/4885NOS1 3870/4885NOS2 4083/4885 |
| US-12384813-B2 | Polymer linked multimers of guanosine-3′, 5′-cyclic monophosphates | PRKG1, PRKG2, PRKAG3 | NOS3 1116/4885NOS1 1920/4885NOS2 1748/4885 |
| US-12371461-B2 | Nemo coiled coil mimics and methods of using same | COIL, CALCOCO2, NCAPH | NOS3 1914/4885NOS1 2370/4885NOS2 2393/4885 |
| US-12485182-B2 | Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair | PDGFA, PDGFRB, TEK | NOS3 2114/4885NOS1 3356/4885NOS2 3488/4885 |
| US-20260083852-A1 | PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR | PDGFA, DCLRE1A, PDGFRA | NOS3 3771/4885NOS1 4059/4885NOS2 3967/4885 |
| US-20260001924-A1 | NEMO COILED COIL MIMICS AND METHODS OF USING SAME | DDX21, PHAX, RBX1 | NOS3 2583/4885NOS1 2359/4885NOS2 3034/4885 |
| US-20220204450-A1 | Orally Active Melanocortin Receptor-4 Compounds | MC4R, MC1R, MC3R | NOS3 3583/4885NOS1 3870/4885NOS2 4083/4885 |
| US-20260116855-A1 | ORALLY ACTIVE MELANOCORTIN RECEPTOR-4 COMPOUNDS | MC1R, MC3R, MC5R | NOS3 1703/4885NOS1 2290/4885NOS2 2831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.