Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214895 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9210803 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL11609820 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL7391537 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2287725 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL2723911 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9202867 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL8714667 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL9211158 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 | |
| SCHEMBL28289397 | 0.97 | TSHR (0.48) | TSHRTHRBFAAHTRPV1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427430-A1 | 5-OXO-ETE RECEPTOR ANTAGONIST COMPOUNDS | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2012-03-14 | — | — | EP | claimed |
| WO-2010127452-A1 | 5-OXO-ETE RECEPTOR ANTAGONIST COMPOUNDS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2010-11-11 | — | — | WO | claimed |
| US-20050101772-A1 | Non-metallocenes, method for the production thereof and the use thereof for the polymerisation of olefins | CELANESE VENTURES GMBH (DE) | 2005-05-12 | — | — | US | claimed |
| US-6277537-B1 | PHENOLIC COMPOUND | EASTMAN KODAK COMPANY | 2001-08-21 | — | — | US | claimed |
| US-5512410-A | Heat image separation with phenolic thermal solvents and dye releasing couplers | EASTMAN KODAK COMPANY (US) | 1996-04-30 | — | — | US | claimed |
| CN-116472174-A | Laminated film for decoration molding, method for producing the film, and decoration molded article | 东洋油墨SC控股株式会社 | 2023-07-21 | — | — | CN | disclosed |
| CN-114874247-A | Boron-nitrogen compound and organic electronic device comprising same | 广州追光科技有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-114751941-A | Binuclear iridium complex and organic electronic device containing same | 广州追光科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-114751940-A | Binuclear iridium complex of pyrazole auxiliary ligand and application thereof | 广州追光科技有限公司 | 2022-07-15 | — | — | CN | disclosed |
| CN-110177822-B | Synthesis of polycarbonate siloxane diol | 奥特克国际公开有限公司 | 2022-06-14 | — | — | CN | disclosed |
| CN-114539273-A | Novel heterocyclic derivatives useful as SHP2 inhibitors | 北京加科思新药研发有限公司 | 2022-05-27 | — | — | CN | disclosed |
| US-20220026803-A1 | RESIST COMPOSITION AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-01-27 | — | — | US | disclosed |
| US-4146540-A | Pyrazole compounds as stabilizers for organic materials | SANDOZ LTD. (CH) | 1979-03-27 | — | — | US | disclosed |
| US-4107138-A | Phosphonous and thiophosphonous acid ethers as stabilizers for organic materials | SANDOZ LTD. (CH) | 1978-08-15 | — | — | US | disclosed |
| US-4101326-A | Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters | EASTMAN KODAK COMPANY (US) | 1978-07-18 | — | — | US | disclosed |
| US-4008200-A | Method of stabilizing organic materials employing pyrazole compounds and stabilized compositions thereof | SANDOZ LTD. (CH) | 1977-02-15 | — | — | US | disclosed |
| US-3987097-A | INCREASING AFFINITY FOR ANIONIC DYES | SANDOZ LTD. (CH) | 1976-10-19 | — | — | US | disclosed |
| US-3975382-A | PYRAZOLONE(5)METAL COMPLEXES AS STABILIZERS FOR ORGANIC MATERIALSULTRAVIOLET RADIATION | SANDOZ LTD. (CH) | 1976-08-17 | — | — | US | disclosed |
| US-3948946-A | Cyclic acetals and mercaptals | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-04-06 | — | — | US | disclosed |
| US-3936479-A | 2-BENZAMIDO-BENZOPHENONES, UV STABILIZERS, PLASTICS | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101772-A1 | Non-metallocenes, method for the production thereof and the use thereof for the polymerisation of olefins | CPNE4, CYP4F12, PPOX | TSHR 4196/4885THRB 4646/4885FAAH 3567/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.