Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.72 |
| ▸ | ITK | Q08881 | 5/20 | 0.72 |
| ▸ | BTK | Q06187 | 4/20 | 0.72 |
| ▸ | JAK2 | O60674 | 1/20 | 0.72 |
| ▸ | LYN | P07948 | 1/20 | 0.72 |
| ▸ | TEC | P42680 | 1/20 | 0.72 |
| ▸ | TXK | P42681 | 1/20 | 0.72 |
| ▸ | BMX | P51813 | 1/20 | 0.72 |
| ▸ | JAK3 | P52333 | 1/20 | 0.72 |
| ▸ | CD69 | Q07108 | 1/20 | 0.72 |
| ▸ | SYK | P43405 | 5/20 | 0.68 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.59 |
| ▸ | CDK2 | P24941 | 2/20 | 0.59 |
| ▸ | CDK9 | P50750 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30843981 | 1.00 | EGFR (0.72) | EGFRITKBTKJAK2LYN | |
| SCHEMBL29411924 | 0.93 | EGFR (0.72) | EGFRITKBTKJAK2LYN | |
| SCHEMBL28718244 | 0.93 | EGFR (0.72) | EGFRITKBTKJAK2LYN | |
| SCHEMBL12518393 | 0.92 | EGFR (0.73) | EGFRITKBTKJAK2LYN | |
| SCHEMBL12518394 | 0.92 | EGFR (0.73) | EGFRITKBTKJAK2LYN | |
| SCHEMBL28720308 | 0.90 | EGFR (0.65) | EGFRITKBTKJAK2LYN | |
| SCHEMBL16178656 | 0.88 | EGFR (0.69) | EGFRITKBTKJAK2LYN | |
| SCHEMBL29431539 | 0.88 | EGFR (0.69) | EGFRITKBTKJAK2LYN | |
| SCHEMBL28960554 | 0.88 | EGFR (0.66) | EGFRITKBTKJAK2LYN | |
| SCHEMBL12518395 | 0.88 | EGFR (0.68) | EGFRITKBTKJAK2LYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181161-B | (2- ((substituted oxy) phenyl) amino) pyrimidin-4-yl) aminobenzoyl derivative and preparation method and application thereof | 南通大学 | 2024-02-27 | — | — | CN | claimed |
| CN-114181161-A | (2- ((substituted oxy) phenyl) amino) pyrimidine-4-yl) aminobenzoyl derivative and preparation method and application thereof | 南通大学 | 2022-03-15 | — | — | CN | claimed |
| CN-114181161-B | (2- ((substituted oxy) phenyl) amino) pyrimidin-4-yl) aminobenzoyl derivative and preparation method and application thereof | 南通大学 | 2024-02-27 | — | — | CN | disclosed |
| CN-114181161-A | (2- ((substituted oxy) phenyl) amino) pyrimidine-4-yl) aminobenzoyl derivative and preparation method and application thereof | 南通大学 | 2022-03-15 | — | — | CN | disclosed |