Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA4 | P22748 | 1/20 | 0.62 |
| ▸ | CA6 | P23280 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL28344048 | 0.87 | ALDH1A1 (0.58) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL11053279 | 0.85 | ALDH1A1 (0.72) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL11590105 | 0.85 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL31230843 | 0.85 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL28399898 | 0.85 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL30340746 | 0.85 | ALDH1A1 (0.78) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL5551628 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylamide SCHEMBL10786324 | 0.84 | KDM4E (0.68) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| Salicylic Acid SCHEMBL11512229 | 0.83 | ALDH1A1 (0.75) | ALDH1A1HPGDKDM4EHMGB1SMN1; SMN2 | |
| SCHEMBL11407944 | 0.83 | TSHR (0.59) | ALDH1A1HPGDKDM4ESMN1; SMN2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114150504-B | Preparation method of rust-proof cover | 安徽马钢和菱实业有限公司 | 2024-01-30 | — | — | CN | claimed |
| CN-114150504-A | Preparation method of antirust cover | 安徽马钢和菱实业有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-114150504-B | Preparation method of rust-proof cover | 安徽马钢和菱实业有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-217497157-U | Dampproofing rust-resistant cover | 安徽马钢和菱实业有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-114150504-A | Preparation method of antirust cover | 安徽马钢和菱实业有限公司 | 2022-03-08 | — | — | CN | disclosed |