Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Salicylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 9/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 9/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 9/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL5551574 | 0.91 | HTT (0.51) | ALDH1A1HTTGRIN1GRIN2AGRIN2B | |
| SCHEMBL5551164 | 0.86 | HTT (0.47) | HTTGRIN1GRIN2AGRIN2BNPC1 | |
| Salicylic Acid SCHEMBL28715028 | 0.85 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4ECA12CA1 | |
| SCHEMBL5547296 | 0.84 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTGRIN1GRIN2A | |
| SCHEMBL5552754 | 0.84 | HTT (0.44) | CA12CA1CA2HMGB1CA4 | |
| Benzoic Acid SCHEMBL5547336 | 0.82 | GRIN1 (0.47) | NAPRTHTTGRIN1GRIN2AGRIN2B | |
| Salicylic Acid SCHEMBL8016662 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL1835140 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL5195824 | 0.81 | KDM4E (0.72) | ALDH1A1HPGDKDM4ECA12CA1 | |
| Salicylic Acid SCHEMBL4464042 | 0.81 | KDM4E (0.72) | ALDH1A1HPGDKDM4ECA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185330-A1 | Liquids | THE UNIVERSITY OF YORK (GB) | 2007-08-09 | — | — | US | claimed |