Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | TACR2 | P21452 | 1/20 | 0.54 |
| ▸ | BCL3 | P20749 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28716273 | 0.90 | SMN1; SMN2 (0.66) | MAPTLMNAPKMALDH1A1MCHR1 | |
| SCHEMBL28701513 | 0.89 | MAPT (0.62) | MAPTLMNAPKMALDH1A1MCHR1 | |
| SCHEMBL28936808 | 0.88 | LMNA (0.57) | MAPTLMNAPKMALDH1A1BCL3 | |
| SCHEMBL28936778 | 0.88 | EPHX2 (0.60) | MAPTLMNAPKMEPHX2NAMPT | |
| SCHEMBL28716279 | 0.88 | EPHX2 (0.60) | MAPTLMNAPKMALDH1A1BCL3 | |
| SCHEMBL28720599 | 0.88 | MAPT (0.80) | MAPTLMNAPKMALDH1A1TACR2 | |
| SCHEMBL28711975 | 0.86 | EPHX2 (0.63) | MAPTLMNAPKMTACR2EPHX2 | |
| SCHEMBL6109229 | 0.82 | MCHR1 (0.77) | MAPTLMNAPKMALDH1A1MCHR1 | |
| SCHEMBL28713910 | 0.81 | POLB (0.57) | LMNAALDH1A1GAABCL3NAMPT | |
| SCHEMBL6109004 | 0.79 | MCHR1 (0.74) | MAPTLMNAPKMALDH1A1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979936-A | 2-aryl ureido-N- [3- (4-morpholinyl) propyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | claimed |
| CN-113979936-A | 2-aryl ureido-N- [3- (4-morpholinyl) propyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | disclosed |