Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28701513 | 0.92 | MAPT (0.62) | EPHX2MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL28716273 | 0.91 | SMN1; SMN2 (0.66) | EPHX2MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL28936808 | 0.91 | LMNA (0.57) | EPHX2MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL28716279 | 0.91 | EPHX2 (0.60) | EPHX2MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL28716265 | 0.88 | MAPT (0.61) | EPHX2MAPTLMNAPKMSMN1; SMN2 | |
| SCHEMBL28711975 | 0.88 | EPHX2 (0.63) | EPHX2MAPTLMNAPKMNAMPT | |
| SCHEMBL28720599 | 0.85 | MAPT (0.80) | EPHX2MAPTLMNAPKM | |
| SCHEMBL28713910 | 0.83 | POLB (0.57) | LMNASMN1; SMN2NAMPT | |
| SCHEMBL30417063 | 0.81 | SMN1; SMN2 (0.85) | EPHX2MAPTLMNASMN1; SMN2CNR1 | |
| SCHEMBL6108922 | 0.78 | MCHR1 (0.73) | EPHX2LMNASMN1; SMN2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113979936-A | 2-aryl ureido-N- [3- (4-morpholinyl) propyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | claimed |
| CN-113979936-A | 2-aryl ureido-N- [3- (4-morpholinyl) propyl ] nicotinamide compound and application thereof | 沈阳药科大学 | 2022-01-28 | — | — | CN | disclosed |