Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097 | 1.00 | LTB4R2 (0.65) | LTB4R2AGTR1 | |
| SCHEMBL8477345 | 0.91 | AGTR1 (0.70) | LTB4R2AGTR1 | |
| SCHEMBL3417 | 0.91 | AGTR1 (0.70) | LTB4R2AGTR1 | |
| SCHEMBL2746 | 0.87 | AGTR1 (0.53) | LTB4R2AGTR1 | |
| SCHEMBL1927 | 0.86 | AGTR1 (0.55) | LTB4R2AGTR1 | |
| SCHEMBL8475874 | 0.85 | LTB4R2 (0.71) | LTB4R2AGTR1 | |
| SCHEMBL1721 | 0.82 | AGTR1 (0.62) | LTB4R2AGTR1 | |
| SCHEMBL2598 | 0.82 | AGTR1 (0.62) | LTB4R2AGTR1 | |
| SCHEMBL8475880 | 0.81 | LTB4R2 (0.69) | LTB4R2AGTR1 | |
| SCHEMBL7271088 | 0.79 | LTB4R2 (0.61) | LTB4R2AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0443983-B1 | Acyl compounds | CIBA GEIGY AG (CH) | 1996-02-28 | — | — | EP | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0443983-A1 | Acyl compounds | CIBA-GEIGY AG (CH) | 1991-08-28 | — | — | EP | disclosed |